What Does Transient Global Amnesia Really Mean? Review of the Literature and Thorough Study of 142 Cases. Quinette P, Guillery-Girard B, Dayan J et al. Transient Global Amnesia: Diffusion-Weighted Imaging Lesions and Cerebrovascular Disease. Optimal Diffusion-Weighted Imaging Protocol for Lesion Detection in Transient Global Amnesia. High-Resolution Diffusion-Weighted Imaging Increases Lesion Detectability in Patients with Transient Global Amnesia. Post-traumatic amnesia, has a history of trauma 6 Psychogenic amnesia, more-so affects semantic memory compared to episodic memory, while TGA is the opposite 6ĭrug-related amnesia, typically has features of encephalopathy 6 Transient epileptic amnesia, typically presents upon waking while TGA does not 6 hippocampal ischemic), typically exists with other neurological deficits 6 Either temporary or permanent, it may be due to physiological factors such as injury or disease (organic amnesia), to substance use (drug-induced amnesia), or to psychological factors such as a traumatic experience (see dissociative amnesia). The condition rarely recurs in ~5% of patients 5,6. These changes generally appear after symptom resolution, and the highest rate of detection is approximately 2 days after symptom onset 6. anterograde amnesia due to bilateral hippocampal damage, the.

These lesions can be bilateral and even multifocal 2-4. ences for recently consumed food in patients with amnesia. Prospective and retrospective studies based on a small number of transient global amnesia patients can detect small punctate regions of abnormally restricted diffusion on DWI/ADC sequences in the CA1 area of the hippocampus (lateral edge of the hippocampal gyrus abutting the temporal horn). Radiographic featuresĬT brain and conventional sequences of MRI brain may show no abnormalities, especially while the patient is symptomatic.

epileptic phenomena, stroke, focal ischemia) have been proposed with no consensus on the exact mechanism 1,6. Most cases show complete resolution of symptoms within a few hours from onset of symptoms 6. Episodic memories are more-so affected than semantic memories 6. AssociationsĪnterograde and partial retrograde amnesia lasting less than 24 hours without any other neurological or congestive symptoms 6. Transient global amnesia is most common in the 50-70 year age range ref.

Anterograde amnesia synonym